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Nutritional and global indexes of progression in dementia: a 12-month prospective study
- Source :
- American journal of Alzheimer's disease and other dementias. 27(7)
- Publication Year :
- 2012
-
Abstract
- Background: To assess the influence of body mass index (BMI) on the progression of dementia. Methods: Sixty elderly outpatients with untreated dementia followed for 12 months. All patients underwent clinical, cognitive, functional, and nutritional assessment at the baseline and after 12 months. Patients were divided into 2 groups by baseline BMI (< or ≥25 kg/m2). Results: Participants with a baseline BMI ≥25 kg/m2 had significantly higher Mini-Mental State Examination (MMSE) scores (21 ± 5.1 vs 15.9 ± 5.5; P < .001), while clinical dementia rating (CDR) and multidimensional prognostic index (MPI) scores were similar in the 2 groups. After 12 months, the MMSE score decreased significantly in both groups compared to the baseline, while the CDR and MPI scores increased significantly for patients with a baseline BMI 2. Conclusion: A BMI cutoff of 25 kg/m2 could be useful for identifying frail patients with dementia who will experience a more rapid global impairment, which could be assessed adequately using multidimensional evaluation tools.
- Subjects :
- Male
medicine.medical_specialty
Pediatrics
Activities of daily living
MEDLINE
Nutritional Status
Neuropsychological Tests
Severity of Illness Index
not known
Body Mass Index
Severity of illness
Activities of Daily Living
Medicine
Dementia
Humans
Prospective Studies
Prospective cohort study
Aged
Aged, 80 and over
Mini–Mental State Examination
medicine.diagnostic_test
business.industry
General Neuroscience
Disease progression
medicine.disease
Psychiatry and Mental health
Clinical Psychology
Physical therapy
Disease Progression
Female
Geriatrics and Gerontology
business
Body mass index
Subjects
Details
- ISSN :
- 19382731
- Volume :
- 27
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- American journal of Alzheimer's disease and other dementias
- Accession number :
- edsair.doi.dedup.....20880f774087a866ff3ec802c9daf555