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Molecular Epidemiology of Dengue Viruses Isolated in Shantou City, China, during 2015-2017
- Source :
- Japanese journal of infectious diseases. 73(4)
- Publication Year :
- 2020
-
Abstract
- Dengue viruses (DENVs) affect tropical and subtropical regions, including the Guangdong province of China. Dengue cases are reported almost every year in Shantou city in the Guangdong province. To understand the molecular characteristics of DENVs isolated in Shantou, we performed a molecular epidemiological study based on the envelope protein (E) gene of the DENVs isolated from the cases. Total 174 serum samples were collected from 174 dengue-suspected patients during 2015-2017. A total of 33.9% (59/174) were diagnosed with dengue. Serotypes of DENVs were identified in 27 samples; 37% (10/27), 55.6% (15/27), 3.7% (1/27), 3.7% (1/27) were serotype 1 DENV (DENV-1), serotype 2 DENV (DENV-2), serotype 3 DENV (DENV-3), and serotype 4 DENV (DENV4), respectively. Genotypes Ⅰ and Ⅳ were detected in DENV-1, while only the Cosmopolitan genotype was detected in DENV-2. The replacement of the predominant serotype (genotype), which takes place every year, implied that the dengue endemic in Shantou might be caused by an imported infection rather than by local populations. Our results suggested that DENVs in Shantou are closely related to the strains circulating in Southeast Asian countries, which were possibly transmitted to Shantou through some relay point cities.
- Subjects :
- 0301 basic medicine
Microbiology (medical)
Serotype
medicine.medical_specialty
China
Genotype
viruses
030106 microbiology
Biology
Southeast asian
Serogroup
Dengue fever
Dengue
03 medical and health sciences
0302 clinical medicine
Epidemiology
medicine
Humans
030212 general & internal medicine
Molecular Epidemiology
Molecular epidemiology
virus diseases
General Medicine
biochemical phenomena, metabolism, and nutrition
Dengue Virus
medicine.disease
Serum samples
Virology
Infectious Diseases
Subjects
Details
- ISSN :
- 18842836
- Volume :
- 73
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Japanese journal of infectious diseases
- Accession number :
- edsair.doi.dedup.....206557e9ef2dc4a27d61ecf44fb3ebc6