Iron and Atherosclerosis: The Link Revisited

Authors :: Suowen Xu
Source :: Trends in molecular medicine. 25(8)
Publication Year :: 2019
Abstract: The causal link between iron and atherosclerosis has been debated. Recent studies have revisited the 'iron hypothesis' by showing that dietary iron overload or elevated non-transferrin bound iron (NTBI) aggravates atherosclerosis in mice by driving vascular dysfunction, thus identifying NTBI as a risk factor and therapeutic target for atherosclerosis.

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