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Enhancing Mood, Cognition, and Quality of Life in Pediatric Multiple Sclerosis
- Source :
- Paediatric Drugs
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Pediatric-onset multiple sclerosis (POMS), representing approximately 5% of all MS cases, affects the central nervous system during its ongoing development. POMS is most commonly diagnosed during adolescence but can occur in younger children as well. For pediatric patients with MS, it is critical to manage the full impact of the disease and monitor for any effects on school and social functioning. Disease management includes not only disease-modifying therapies but also strategies to optimize wellbeing. We review the interventions with the highest evidence of ability to improve the disease course and quality of life in POMS. High levels of vitamin D and a diet low in saturated fat are associated with lower relapse rates. Exercise ameliorates fatigue and sleep. Behavioral strategies for sleep hygiene and mood regulation can also improve fatigue and perceived health. POMS management should be addressed holistically, including assessing overall symptom burden as well as the psychological and functional impact of the disease.
- Subjects :
- Multiple Sclerosis
Adolescent
Saturated fat
Psychological intervention
Medical Marijuana
Leading Article
Disease
Antioxidants
03 medical and health sciences
Cognition
0302 clinical medicine
Quality of life (healthcare)
Humans
Medicine
Pharmacology (medical)
Longitudinal Studies
Vitamin D
Disease management (health)
Child
Exercise
Fatigue
030203 arthritis & rheumatology
Sleep hygiene
business.industry
Multiple sclerosis
Disease Management
medicine.disease
Affect
Mood
Pediatrics, Perinatology and Child Health
Quality of Life
business
030217 neurology & neurosurgery
Clinical psychology
Subjects
Details
- ISSN :
- 11792019 and 11745878
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Pediatric Drugs
- Accession number :
- edsair.doi.dedup.....1fc8711a446c7032c255d589d9df36fa