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Dosimetry of MammoSite® applicator: Comparison between Monte Carlo simulation, measurements, and treatment planning calculation
- Source :
- Journal of Cancer Research and Therapeutics, Vol 9, Iss 2, Pp 224-229 (2013)
- Publication Year :
- 2013
- Publisher :
- Wolters Kluwer Medknow Publications, 2013.
-
Abstract
- Purpose: To investigate the dosimetric characteristics of accelerated partial breast irradiation technique by MammoSite® applicator using thermoluminescent dosimeter (TLD) and Monte Carlo simulation to comparing them with treatment planning system calculation for planning target volume (PTV) and organs at risk such as skin, lung and chest wall. Materials and Methods: The Monte Carlo MCNP-5 code was used to simulate dose rate in the PTV that is a MammoSite® balloon with 1 cm margin around it. Experimental dosimetry was carried out within a female-equivalent chest phantom with TLD dosimeter after insertion of 192 Ir source into the MammoSite® applicator. Three dimensional planning (TP) was done for dose delivery to the specific points within the phantom by means of FlexiPlan software. Results: Statistical comparisons were done between TP calculation, Monte Carlo simulation and TLD. Our results showed good agreement for surface doses between simulation and measurement. The mean skin dose for the simulation and TLD result was 61.7% and 56.8% of prescription dose, respectively. The maximum dose to the chest wall for Monte Carlo and TLD were 114.4% and 111.8% of prescription dose, respectively. The maximum dose to the lung for Monte Carlo and TLD results were 28.4% and 27.3% of prescription dose, respectively. Using Monte Carlo simulation and an average female chest phantom, it was possible to demonstrate the accuracy on the calculated dose rate in the PTV of a MammoSite® dose delivery system with 192 Ir HDR sources. Conclusions: The results showed acceptable agreement between simulation, treatment planning, and experimental dosimetry results.
- Subjects :
- treatment planning
medicine.medical_treatment
Monte Carlo method
Brachytherapy
Planning target volume
192 Ir
Breast Neoplasms
lcsh:RC254-282
Imaging phantom
Medicine
Dosimetry
Humans
thermoluminesce dosimeter
Radiology, Nuclear Medicine and imaging
Computer Simulation
Radiation treatment planning
MammoSite®
business.industry
Phantoms, Imaging
Radiotherapy Planning, Computer-Assisted
Mont Carlo simulation
Radiotherapy Dosage
General Medicine
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Oncology
Female
Thermoluminescent Dosimetry
Thermoluminescent dosimeter
business
Nuclear medicine
Dose rate
Monte Carlo Method
Subjects
Details
- Language :
- English
- ISSN :
- 19984138 and 09731482
- Volume :
- 9
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of Cancer Research and Therapeutics
- Accession number :
- edsair.doi.dedup.....1f8a9bc0743545176e20c50df8829bb4