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Only a Rapid Complete Biochemical Remission After 131I-Therapy is Associated with an Unimpaired Life Expectancy in Differentiated Thyroid Cancer
- Source :
- Hormone and Metabolic Research. 49:860-868
- Publication Year :
- 2017
- Publisher :
- Georg Thieme Verlag KG, 2017.
-
Abstract
- The objective of the work was to investigate the relationship between thyroglobulin doubling time (TgDT) as a marker of speed of response to 131I-therapy and the differentiated thyroid cancer (DTC) recurrence rate, DTC specific mortality rate, and relative survival rate in a DTC population followed over a long period of time after 131I-therapy. From our database, data of 1354 patients were reviewed. TgDT could be calculated in 174 patients, however, 376 patients did not have sufficient Tg values available for TgDT calculation and 804 patients reached biochemical remission before a sufficient number of Tg measurements for TgDT calculation was acquired. Main outcome measures were recurrence-free, DTC specific, and relative survival rates. In patients
- Subjects :
- Adult
Male
medicine.medical_specialty
Multivariate analysis
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
Clinical Biochemistry
Population
030209 endocrinology & metabolism
Kaplan-Meier Estimate
Disease
Thyroglobulin
Biochemistry
Iodine Radioisotopes
03 medical and health sciences
Life Expectancy
0302 clinical medicine
Endocrinology
Internal medicine
medicine
Humans
Doubling time
Thyroid Neoplasms
education
Thyroid cancer
Aged
education.field_of_study
Relative survival
business.industry
Remission Induction
Biochemistry (medical)
General Medicine
Middle Aged
Prognosis
medicine.disease
030220 oncology & carcinogenesis
Multivariate Analysis
Female
business
Progressive disease
Subjects
Details
- ISSN :
- 14394286 and 00185043
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Hormone and Metabolic Research
- Accession number :
- edsair.doi.dedup.....1f2e883234c443922a5c2e650561c188