Measuring the global, regional, and national burden of type 2 diabetes and the attributable risk factors in all 194 countries

No detailed quantitative global, regional, or national estimates of the disability-adjusted life years (DALYs) of type 2 diabetes mellitus (T2DM) are available.We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 to estimate the global, regional, and national incidence rates and DALYs of T2DM, as well as the associated risk factors, in all 194 countries and territories by age, sex, and sociodemographic status during the period from 2007 to 2017.Globally, the age-standardized incidence and DALY rates increased by 3.23% and 5.07% during 2007 to 2017, respectively. The age-standardized incidence and DALY rates in 2017 and the corresponding percentage changes during 2007 to 2017 were highest in the low-middle sociodemographic index (SDI) quintile. Regionally, the highest 2017 age-standardized incidence and DALY rates were observed in Oceania, whereas the largest percentage increases in both rates during 2007 to 2017 were observed in Southeast Asia. Nationally, Iran, the United Kingdom, and Indonesia reported the largest percentage increases in the age-standardized incidence rates, whereas Georgia, Czech Republic, and Iran showed the largest percentage increases in the age-standardized DALY rates. Globally, the largest percentage increases in risk-attributable DALYs were associated with a high body mass index, low physical activity level, high fasting plasma glucose level, and high sugar-sweetened beverage and red meat consumption.The global T2DM age-standardized incidence and DALY rates increased globally between 2007 and 2017, especially in the low-middle SDI quintile, Southeast Asia.背景: 目前尚无关于2型糖尿病 (T2DM) 的残疾调整生命年 (DALY) 的详细的全球、区域或国家定量估计值。 方法: 我们使用 2017 年全球疾病负担、伤害和风险因素研究 (GBD) 的数据来估计所有 194个国家的 T2DM 发病率和 DALYs 以及 2007 年至 2017 年期间按年龄、性别和社会人口状况划分的地区相关的风险因素。 结果: 在全球范围内, 2007年至 2017年的年龄标准化发病率和 DALY 率分别增加了 3.23% 和 5.07%。 2017 年的年龄标准化发病率和 DALY 率以及 2007 年至 2017 年期间的相应百分比变化在中低收入国家中最高。从区域来看, 2017 年年龄标准化发病率和 DALY 率最高的是大洋洲, 而 2007 年至 2017 年期间, 东南亚的百分比增幅最大。在全国范围内, 伊朗、英国和印度尼西亚的年龄标准化发病率百分比增幅最大, 而格鲁吉亚、捷克共和国和伊朗的年龄标准化 DALY 比率增幅最大。在全球范围内, 可归因于风险的 DALY 的最大百分比增加与高体重指数、低体力活动水平、高空腹血糖水平以及高含糖饮料和红肉消费相关。 结论: 2007 年至 2017 年间, T2DM 年龄标准化发病率和 DALY 率在全球范围内增加, 尤其是在东南亚中低收入国家。.