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TRY : A phase II study to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small cell lung cancer (NSCLC) with HER2 overexpression or amplification or mutation

Authors :
Marcel Wiesweg
Marc Bos
Monika Serke
Lucia Nogova
Henning Reis
Christian Mattonet
Gernot Schoch
Wilfried Eberhardt
Martin Schuler
Matthias Scheffler
Hans-Ulrich Schildhaus
Uwe Fuhr
Lukas C. Heukamp
Juergen Wolf
Masyar Gardizi
Reinhard Buettner
Yon-Dschun Ko
Kurt Werner Schmid
Publication Year :
2014

Abstract

8109 Background: HER2 amplifications and/or mutations are rare genetic alterations in NSCLC accounting for approximately 4%. Preliminary clinical data suggested efficacy of trastuzumab (Herceptin) ...

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....1f077735a70d76fe343546951c099096