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The clinical relevance of the microbiome when managing paediatric infectious diseases—Narrative review
- Source :
- Acta Paediatrica. 110:441-449
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- In recent years, the field of infectious diseases has been hit by the overwhelming amount of information generated while the human microbiome is being disentangled. Based on the interaction between the microbiota and the immune system, the implications regarding infectious diseases are probably major and remain a challenge. Aims This review was conceived as a comprehensive tool to provide an overview of the available evidence regarding the influence of the microbiome on infectious diseases in children. Methods We present the main findings aroused from microbiome research in prevention, diagnosis and treatment of infectious disease under a paediatric perspective, to inform clinicians of the potential relevance of microbiome-related knowledge for translation to clinical practice. Results and conclusion The evidence shown in this review highlights the numerous research gaps ahead and supports the need to move forward to integrating the so-called microbiome thinking into our routine clinical practice.
- Subjects :
- medicine.medical_specialty
business.industry
Microbiota
Human microbiome
General Medicine
Communicable Diseases
Paediatric infectious diseases
Clinical Practice
03 medical and health sciences
0302 clinical medicine
Infectious disease (medical specialty)
030225 pediatrics
Pediatrics, Perinatology and Child Health
medicine
Humans
Clinical significance
Narrative review
Routine clinical practice
030212 general & internal medicine
Microbiome
Child
Intensive care medicine
business
Subjects
Details
- ISSN :
- 16512227 and 08035253
- Volume :
- 110
- Database :
- OpenAIRE
- Journal :
- Acta Paediatrica
- Accession number :
- edsair.doi.dedup.....1effda6e816e214e1297a014e839cb29