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In-hospital Delay of Appendectomy in Acute, Complicated Appendicitis

Authors :
Bolmers, M. D. M.
de Jonge, J.
Bom, W. J.
van Rossem, C. C.
van Geloven, A. A. W.
Bemelman, W. A.
van Acker, G. J.
Akkermans, B.
Akkersdijk, G. J.
Algie, G. D.
Allema, J. H.
Andeweg, C. S.
Appeldoorn, N.
van Baal, J. G.
Bakker, C. M. den
Bartels, S. A.
van den Berg, C.
Boekestijn, B.
Boer, F. C. den
Boerma, D.
van den Boom, A. L.
Boute, M. C.
Bouwense, S. A.
Bransen, J.
van Brussel, F. A.
Busch, O. R.
de Castro, S. M.
Cense, H. A.
Croese, C.
van dalen, T.
Dawson, I.
van Dessel, E.
Dettmers, R.
Dhar, N.
Dohmen, F. Y.
van Dongen, K. W.
van Duijvendijk, P.
Dulfer, R. R.
Dwars, B. J.
Eerenberg, J. P.
van der Elst, M.
van den Ende, E.
Fassaert, L. M.
Fikkers, J. T.
Foppen, J. W.
Furnee, E. J.
Garssen, F. P.
Gerhards, M. F.
van Goor, H.
de Graaf, J. S.
Graat, L. J.
Grootr, J.
van der Ham, A. C.
Hamming, J. F.
Hamminga, J. T.
van der Harst, E.
Heemskerk, J.
Heijne, A.
Heikens, J. T.
Heineman, E.
Hertogs, R.
van Heurn, E.
van den Hil, L. C.
Hooftwijk, A. G.
Hulsker, C. C.
Hunen, D. R.
Ibelings, M. S.
Klaase, J. M.
Klicks, R.
Knaapen, L.
Kortekaas, R. T.
Kruyt, F.
Kwant, S.
Lases, S. S.
Lettinga, T.
Loupatty, A.
Matthijsen, R. A.
Minnee, R. C.
Mirck, B.
Mitalas, L.
Moes, D.
Moorman, A. M.
Nieuwenhuijs, V. B.
Nieuwenhuizen, G. A.
Nijk, P. D.
Omloo, J. M.
Ottenhof, A. G.
Palamba, H. W.
van der Peet, D. L.
Pereboom, I. T.
Plaisier, P. W.
van der Ploeg, A. P.
Raber, M. H.
Reijen, M. M.
Rijna, H.
Rosman, C.
Roumen, R. M.
Scmitz, R. F.
Schouten van der Velden, A. P.
Scheurs, W. H.
Sigterman, T. A.
Smeets, H. J.
Sonnevled, D. J.
Sosef, M. N.
Spoor, S. F.
Stassen, L. P.
van Steensel, L.
Stortelder, E.
Straatman, J.
van Susante, H. J.
Suykerbuyk de Hoog, D. E.
Terwisscha van Scheltinga, C.
Toorenvliet, B. R.
Verbeek, P. C.
Verseveld, M.
Volders, J. H.
Vriens, M. R.
Vriens, P. W.
Vrouenraets, B. C.
van de wall, B. J.
Wegdam, J. A.
Westerduin, E.
Wever, J. J.
Wijfels, N. A.
Wijnhoven, B. P.
Winkel, T. A.
van der Zee, D. C.
Zeillemaker, A. M.
Zietse, C.
Amsterdam Reproduction & Development (AR&D)
Pediatrics
AGEM - Re-generation and cancer of the digestive system
CCA - Cancer Treatment and quality of life
Other Research
Surgery
Amsterdam Gastroenterology Endocrinology Metabolism
Graduate School
AII - Infectious diseases
AGEM - Amsterdam Gastroenterology Endocrinology Metabolism
Paediatric Surgery
ARD - Amsterdam Reproduction and Development
Source :
Journal of Gastrointestinal Surgery, 26(5), 1063-1069. Springer New York, Journal of Gastrointestinal Surgery, 26, 5, pp. 1063-1069, Journal of gastrointestinal surgery, 26(5), 1063-1069. Springer New York, Bolmers, M D M, de Jonge, J, Bom, W J, van Rossem, C C, van Geloven, A A W, Bemelman, W A, On behalf of the Snapshot Appendicitis Collaborative Study group, van Acker, G J, Akkermans, B, Akkersdijk, G J, Algie, G D, Allema, J H, Andeweg, C S, Appeldoorn, N, van Baal, J G, Bakker, C M D, Bartels, S A, van den Berg, C, Boekestijn, B, Boer, F C D, Boerma, D, van den Boom, A L, Boute, M C, Bouwense, S A, Bransen, J, van Brussel, F A, Busch, O R, de Castro, S M, Cense, H A, Croese, C, van dalen, T, Dawson, I, van Dessel, E, Dettmers, R, Dhar, N, Dohmen, F Y, van Dongen, K W, van Duijvendijk, P, Dulfer, R R, Dwars, B J, Eerenberg, J P, van der Elst, M, van den Ende, E, Fassaert, L M, Fikkers, J T, Foppen, J W, Furnee, E J, Garssen, F P, Gerhards, M F, van Goor, H, de Graaf, J S, Graat, L J, Grootr, J, van der Ham, A C, Hamming, J F, Hamminga, J T, van der Harst, E, Heemskerk, J, Heijne, A, Heikens, J T, Heineman, E, Hertogs, R, van Heurn, E, van den Hil, L C, Hooftwijk, A G, Hulsker, C C, Hunen, D R, Ibelings, M S, Klaase, J M, Klicks, R, Knaapen, L, Kortekaas, R T, Kruyt, F, Kwant, S, Lases, S S, Lettinga, T, Loupatty, A, Matthijsen, R A, Minnee, R C, Mirck, B, Mitalas, L, Moes, D, Moorman, A M, Nieuwenhuijs, V B, Nieuwenhuizen, G A, Nijk, P D, Omloo, J M, Ottenhof, A G, Palamba, H W, van der Peet, D L, Pereboom, I T, Plaisier, P W, van der Ploeg, A P, Raber, M H, Reijen, M M, Rijna, H, Rosman, C, Roumen, R M, Scmitz, R F, Schouten van der Velden, A P, Scheurs, W H, Sigterman, T A, Smeets, H J, Sonnevled, D J, Sosef, M N, Spoor, S F, Stassen, L P, van Steensel, L, Stortelder, E, Straatman, J, van Susante, H J, Suykerbuyk de Hoog, D E, Terwisscha van Scheltinga, C, Toorenvliet, B R, Verbeek, P C, Verseveld, M, Volders, J H, Vriens, M R, Vriens, P W, Vrouenraets, B C, van de wall, B J, Wegdam, J A, Westerduin, E, Wever, J J, Wijfels, N A, Wijnhoven, B P, Winkel, T A, van der Zee, D C, Zeillemaker, A M & Zietse, C 2022, ' In-hospital Delay of Appendectomy in Acute, Complicated Appendicitis ', Journal of Gastrointestinal Surgery, vol. 26, no. 5, pp. 1063-1069 . https://doi.org/10.1007/s11605-021-05220-w, Journal of Gastrointestinal Surgery, 26, 1063-1069
Publication Year :
2022

Abstract

Item does not contain fulltext BACKGROUND: Present theory is that uncomplicated and complicated appendicitis are different entities. Recent studies suggest it is safe to delay surgery in patients with uncomplicated appendicitis. We hypothesize that patients with complicated appendicitis are at higher risk for postoperative complications when surgery is delayed. METHODS: Data was used from the multicenter, prospective SNAPSHOT appendicitis study of 1975 patients undergoing surgery for suspected appendicitis. Adult patients (≥ 18 years) who underwent appendectomy for appendicitis were included in this study. The primary outcome was the difference in postoperative complications between patients with complicated appendicitis who were operated within and after 8 h after hospital presentation. Secondary outcomes were the incidence of both uncomplicated and complicated appendicitis in relationship to delay of appendectomy. Follow-up was 30 days. A multivariable analysis was performed. RESULTS: Of 1341 adult patients with appendicitis, 34.3% had complicated appendicitis. In patients with complicated appendicitis, 22.8% developed a postoperative complication compared to 8.2% for uncomplicated appendicitis (P 8 h) increased the complication rate in patients with complicated appendicitis (28.1%) compared to surgery within 8 h (18.3%; P = 0.01). Multivariate analysis showed a delay in surgery as an independent predictor for a postoperative complication in patients with complicated appendicitis (OR 1.71; 95%CI 1.01-2.68, P = 0.02). CONCLUSION: In-hospital delay of surgery (> 8 h) in patients with complicated appendicitis is associated with a higher risk of a postoperative complication. It is important that we recognize and treat these patients early.

Details

Language :
English
ISSN :
1091255X
Database :
OpenAIRE
Journal :
Journal of Gastrointestinal Surgery, 26(5), 1063-1069. Springer New York, Journal of Gastrointestinal Surgery, 26, 5, pp. 1063-1069, Journal of gastrointestinal surgery, 26(5), 1063-1069. Springer New York, Bolmers, M D M, de Jonge, J, Bom, W J, van Rossem, C C, van Geloven, A A W, Bemelman, W A, On behalf of the Snapshot Appendicitis Collaborative Study group, van Acker, G J, Akkermans, B, Akkersdijk, G J, Algie, G D, Allema, J H, Andeweg, C S, Appeldoorn, N, van Baal, J G, Bakker, C M D, Bartels, S A, van den Berg, C, Boekestijn, B, Boer, F C D, Boerma, D, van den Boom, A L, Boute, M C, Bouwense, S A, Bransen, J, van Brussel, F A, Busch, O R, de Castro, S M, Cense, H A, Croese, C, van dalen, T, Dawson, I, van Dessel, E, Dettmers, R, Dhar, N, Dohmen, F Y, van Dongen, K W, van Duijvendijk, P, Dulfer, R R, Dwars, B J, Eerenberg, J P, van der Elst, M, van den Ende, E, Fassaert, L M, Fikkers, J T, Foppen, J W, Furnee, E J, Garssen, F P, Gerhards, M F, van Goor, H, de Graaf, J S, Graat, L J, Grootr, J, van der Ham, A C, Hamming, J F, Hamminga, J T, van der Harst, E, Heemskerk, J, Heijne, A, Heikens, J T, Heineman, E, Hertogs, R, van Heurn, E, van den Hil, L C, Hooftwijk, A G, Hulsker, C C, Hunen, D R, Ibelings, M S, Klaase, J M, Klicks, R, Knaapen, L, Kortekaas, R T, Kruyt, F, Kwant, S, Lases, S S, Lettinga, T, Loupatty, A, Matthijsen, R A, Minnee, R C, Mirck, B, Mitalas, L, Moes, D, Moorman, A M, Nieuwenhuijs, V B, Nieuwenhuizen, G A, Nijk, P D, Omloo, J M, Ottenhof, A G, Palamba, H W, van der Peet, D L, Pereboom, I T, Plaisier, P W, van der Ploeg, A P, Raber, M H, Reijen, M M, Rijna, H, Rosman, C, Roumen, R M, Scmitz, R F, Schouten van der Velden, A P, Scheurs, W H, Sigterman, T A, Smeets, H J, Sonnevled, D J, Sosef, M N, Spoor, S F, Stassen, L P, van Steensel, L, Stortelder, E, Straatman, J, van Susante, H J, Suykerbuyk de Hoog, D E, Terwisscha van Scheltinga, C, Toorenvliet, B R, Verbeek, P C, Verseveld, M, Volders, J H, Vriens, M R, Vriens, P W, Vrouenraets, B C, van de wall, B J, Wegdam, J A, Westerduin, E, Wever, J J, Wijfels, N A, Wijnhoven, B P, Winkel, T A, van der Zee, D C, Zeillemaker, A M & Zietse, C 2022, ' In-hospital Delay of Appendectomy in Acute, Complicated Appendicitis ', Journal of Gastrointestinal Surgery, vol. 26, no. 5, pp. 1063-1069 . https://doi.org/10.1007/s11605-021-05220-w, Journal of Gastrointestinal Surgery, 26, 1063-1069
Accession number :
edsair.doi.dedup.....1ece606e42c143afa7f72ff775ae031e
Full Text :
https://doi.org/10.1007/s11605-021-05220-w