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Common First-Pass CT Angiography Findings Associated With Rapid Growth Rate in Abdominal Aorta Aneurysms Between 3 and 5 cm in Largest Diameter
- Source :
- AJR. American journal of roentgenology. 210(2)
- Publication Year :
- 2017
-
Abstract
- The purpose of this study was to describe CT angiography (CTA) findings of lumen contrast heterogeneity and intraluminal thrombus volume and to evaluate their relationship with rapid aneurysm growth in patients with abdominal aortic aneurysms (AAA) between 3 and 5 cm.This institutional review board-approved and HIPAA-compliant single-center retrospective study included CTA studies obtained between January 2004 and December 2014 in 140 patients with AAA (101 men, 39 women; mean age ± SD, 70 ± 9 years old; age range, 22-87 years old). Standardized measurements for aneurysm intraluminal thrombus volume and a relatively new metric termed "lumen contrast heterogeneity" were obtained from the CTA images. AAA growth rate data were acquired from all subsequent cross-sectional studies. The association between the imaging findings and rapid aneurysm growth (0.4 cm/y) was evaluated using multivariate logistic regression. Patient comorbidities and medications were added to the regression model to assess for further associations with rapid growth rate.Using a baseline logistic regression model, lumen contrast heterogeneity (odds ratio [OR], 1.16; 95% CI, 1.05-1.32), intraluminal thrombus volume (OR, 2.15; 95% CI, 1.26-3.86), and maximum AAA diameter (OR, 1.69; 95% CI, 1.03-2.84) were independently associated with increased likelihood of rapid aneurysm growth. None of the patient comorbidities or medications were significantly associated with the outcome when added to the baseline model.Both intraluminal thrombus and lumen contrast heterogeneity are seen on AAA CTA studies and can be quantified; both of these metrics are independently associated with rapid growth rate and should be recognized by radiologists evaluating patients with AAA during surveillance.
- Subjects :
- Adult
Male
medicine.medical_specialty
Computed Tomography Angiography
Lumen (anatomy)
Comorbidity
030204 cardiovascular system & hematology
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Aneurysm
medicine.artery
Medicine
Intraluminal thrombus
Humans
Radiology, Nuclear Medicine and imaging
In patient
cardiovascular diseases
Aged
Retrospective Studies
First pass
Aged, 80 and over
medicine.diagnostic_test
business.industry
Abdominal aorta
Retrospective cohort study
General Medicine
Middle Aged
medicine.disease
Cross-Sectional Studies
Angiography
cardiovascular system
Disease Progression
Female
Radiology
business
Aortic Aneurysm, Abdominal
Subjects
Details
- ISSN :
- 15463141
- Volume :
- 210
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- AJR. American journal of roentgenology
- Accession number :
- edsair.doi.dedup.....1e98e9957ea2b4c47b6304053a09e4d3