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TheYGR194c(XKS1) gene encodes the xylulokinase from the budding yeastSaccharomyces cerevisiae
- Source :
- FEMS Microbiology Letters. 162:155-160
- Publication Year :
- 1998
- Publisher :
- Oxford University Press (OUP), 1998.
-
Abstract
- We report the finding of a Saccharomyces cerevisiae gene necessary for growth in culture media with D-xylulose as the sole carbon source. This gene corresponds to the YGR194c open reading frame that we have previously described, and it is renamed now XKS1. Data bank comparisons of the protein encoded by the XKS1 gene showed significant homology with different xylulokinases, indicating a possible role in xylulose phosphorylation. The wild-type gene in a centromeric plasmid complemented defective growth of xks1 S. cerevisiae mutant strains in xylulose. By contrast, overexpression negatively influenced cell growth in this carbon source.
- Subjects :
- Genes, Fungal
Molecular Sequence Data
Saccharomyces cerevisiae
Mutant
Gene Expression
Microbiology
Homology (biology)
Open Reading Frames
Xylulose
chemistry.chemical_compound
Genetics
Amino Acid Sequence
Cloning, Molecular
Molecular Biology
Gene
Sequence Deletion
Sequence Homology, Amino Acid
biology
biology.organism_classification
Yeast
Phosphotransferases (Alcohol Group Acceptor)
Open reading frame
chemistry
Xylulokinase
Subjects
Details
- ISSN :
- 15746968 and 03781097
- Volume :
- 162
- Database :
- OpenAIRE
- Journal :
- FEMS Microbiology Letters
- Accession number :
- edsair.doi.dedup.....1e8b9585c61f02e93d1c337ec3d2f523