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RNA - ligand interactions:(I) magnesium binding sites in yeast tRNAPhe
- Source :
- Nucleic Acids Research. 4:2811-2820
- Publication Year :
- 1977
- Publisher :
- Oxford University Press (OUP), 1977.
-
Abstract
- X-ray crystallagraphic studies studies indicate that there are at least four site-specifically bound hydrated Mg2+ ions, [Mg(H2O)n]2+, in yeast tRNAPhe. The size and the octahedral coordination geometry, rather than the charge, of [Mg(H2O)N]2+ appear to be the primary reasons for the specificity of magnesium ions in site-binding and in the stabilization of the tertiary structure of tRNA.
- Subjects :
- Models, Molecular
Binding Sites
Chemical Phenomena
Ligand
Magnesium
Phenylalanine
RNA
chemistry.chemical_element
Saccharomyces cerevisiae
Biology
Ligands
Protein tertiary structure
Chemistry
Crystallography
RNA, Transfer
X-Ray Diffraction
Biochemistry
chemistry
Transfer RNA
Genetics
Nucleic Acid Conformation
Binding site
Magnesium ion
Coordination geometry
Subjects
Details
- ISSN :
- 13624962 and 03051048
- Volume :
- 4
- Database :
- OpenAIRE
- Journal :
- Nucleic Acids Research
- Accession number :
- edsair.doi.dedup.....1e7fd3711c26a870728a045fd2de9270