Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor

Authors :: Michela Puxeddu
Jianchao Wu
Ruoli Bai
Michele D’Ambrosio
Marianna Nalli
Antonio Coluccia
Simone Manetto
Alessia Ciogli
Domiziana Masci
Andrea Urbani
Cinzia Fionda
Sonia Coni
Rosa Bordone
Gianluca Canettieri
Chiara Bigogno
Giulio Dondio
Ernest Hamel
Te Liu
Romano Silvestri
Giuseppe La Regina
Source :: Journal of medicinal chemistry. 65(23)
Publication Year :: 2022
Abstract: We synthesized new aroyl diheterocyclic pyrrole (ARDHEP)

Subjects :: Ovarian Neoplasms
Mice
Tubulin
Cell Line, Tumor
Drug Discovery
Molecular Medicine
Humans
Animals
Female
Pyrroles
Apoptosis
Tubulin Modulators

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