CHRONIC DPP-4 INHIBITION BY SITAGLIPTIN IMPROVES GLOBAL MYOCARDIAL FUNCTION DURING DOBUTAMINE STRESS IN TYPE 2 DIABETES MELLITUS AND CORONARY ARTERY DISEASE

Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted by the gut in response to the oral ingestion of nutrients. GLP-1 has a number of extrapancreatic functions, including enhancing myocardial glucose uptake, that may improve myocardial tolerance to ischemia. The degradation of the active