TPM3-NTRK1 fusion in a pleomorphic xanthoastrocytoma presenting with haemorrhage in a child

A previously healthy 6-year-old boy presented with acute onset of headache, vomiting and right sided weakness. CT imaging was performed which revealed an intracerebral left-sided 7 cm haemorrhagic mass associated with midline shift ([figure 1][1]). The patient subsequently developed signs of