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Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression

Authors :
Marie C. Hasselluhn
Elisabeth Hessmann
Geske Schmidt
Volker Ellenrieder
Steven A. Johnsen
Source :
Cell Death & Disease, Cell Death and Disease, Vol 10, Iss 6, Pp 1-14 (2019)
Publication Year :
2019

Abstract

Given its aggressive tumor biology and its exceptional therapy resistance, pancreatic ductal adenocarcinoma (PDAC) remains a major challenge in cancer medicine and is characterized by a 5-year survival rate of

Details

Language :
English
Database :
OpenAIRE
Journal :
Cell Death & Disease, Cell Death and Disease, Vol 10, Iss 6, Pp 1-14 (2019)
Accession number :
edsair.doi.dedup.....1e042a4c5e7f8191b6f8a8a24b5b0e7d