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Figure S1-S6 from Cisplatin Increases Sensitivity to FGFR Inhibition in Patient-Derived Xenograft Models of Lung Squamous Cell Carcinoma

Authors :
Marie-Liesse Asselin-Labat
Benjamin Solomon
Christopher J. Burns
Matthew E. Ritchie
Prudence A. Russell
Gavin M. Wright
Daniel P. Steinfort
Louis B. Irving
Phillip Antippa
Stephen B. Fox
Jean-Marc Garnier
Stephen B. Ma
Richard J. Young
Aliaksei Z. Holik
Clare E. Weeden
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Fig. S1. Generation of patient-derived xenografts from surgery and biopsy specimens of non small cell lung cancer Supplementary Fig. S2. Squamous cell carcinoma patient-derived xenografts recapitulate the genomic phenotype of patients'' tumors Supplementary Fig. S3. Analysis of biomarkers of response to FGFR inhibition Supplementary Fig. S4. High FGFR1 RNA expression does not predict patient outcome Supplementary Fig. S5. PIK3CA amplification does not predict response to PI3K inhibitors Supplementary Fig. S6. FGFR targeted therapy in FGFR inhibitor resistant tumors does not increase cisplatin sensitivity

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....1e032a8b230e4a781e7789fe34b56e4c