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Oral ulcer activity in Behcet’s disease: Poor medication adherence is an underestimated risk factor
- Source :
- European Journal of Rheumatology. 4:109-112
- Publication Year :
- 2017
- Publisher :
- AVES Publishing Co., 2017.
-
Abstract
- Objective: The aim of this study was to evaluate the relationship between oral ulcer activity and medication adherence according to gender in Behcet's disease (BD) patients. Material and Methods: The study group included 330 BD patients (F/M: 167/163, mean age: 38.5 +/- 10.5 years). Oral ulcer activity and medication adherence were evaluated in the previous month. Medication adherence was evaluated using the 8-item Morisky Medication Adherence Scale (MMAS-8) having a score range of 0 to 8 with high scores indicating better adherence. Low adherence was defined as < 6 points on MMAS-8. Results: Over half of the group had active oral ulcers (n= 219, 66.4%) within the month preceding the visit. The number of oral ulcers was significantly higher in female patients with low medication adherence (2.39 +/- 3.24) than in the rest of the female group (1.28 +/- 2.05; p= 0.023). Although a similar trend was also observed in male patients (2.14 +/- 3.3 vs. 1.81 +/- 2.31), a significant relationship was not observed (p= 0.89). The frequency of medication intake per day was lower in patients with high medication adherence than in the rest of the study group (p= 0.04). Conclusion: Low medication adherence is a hidden risk factor in the management of BD. Poor adherence was associated with oral ulcer activity in female BD patients.
- Subjects :
- NONADHERENCE
medicine.medical_specialty
QUESTIONNAIRE
Medication adherence
Female group
Disease
Behcet's disease
PREDICTIVE-VALIDITY
03 medical and health sciences
0302 clinical medicine
Internal medicine
Female patient
MANAGEMENT
medicine
In patient
030212 general & internal medicine
Risk factor
Oral ulcers
030203 arthritis & rheumatology
COLCHICINE
business.industry
medicine.disease
oral ulcer
RHEUMATOID-ARTHRITIS
CROSS-CULTURAL ADAPTATION
Original Article
business
Subjects
Details
- ISSN :
- 21484279 and 21479720
- Volume :
- 4
- Database :
- OpenAIRE
- Journal :
- European Journal of Rheumatology
- Accession number :
- edsair.doi.dedup.....1dd1cece5cc8c187659a327625d69660