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Prevalence of high-sensitivity cardiac troponin T in real-life cohorts of psoriatic arthritis and general population: a cross-sectional study
- Source :
- Rheumatology international. 40(3)
- Publication Year :
- 2019
-
Abstract
- Patients with psoriatic arthritis (PsA) are at increased risk of cardiovascular disease (CVD). High-sensitivity cardiac troponin T (hs-cTnT) is a novel biomarker of CVD. The objective of this study is to determine the prevalence of circulating hs-cTnT in patients with PsA compared to the general population and to characterize a PsA subset with detectable hs-cTnT. A cross-sectional analysis of serum hs-cTnT levels was performed in 116 consecutive patients with PsA and the Tel-Aviv Medical Center Inflammatory Survey cohort of the general population (n = 6052) as a control group. The level and prevalence of hs-cTnT (ng/L) were similar in the entire study population: 4.94 ± 4.4, 30.2% in PsA, 5.17 ± 6.7, 34.2% and 5.38 ± 4.3, 37.9% in unmatched and matched control groups according to age, gender and cardiovascular risk factors, respectively. Factors associated with detectable hs-cTnT in PsA included male gender (p = 0.002), age (p = 0.007), hypertension (p
- Subjects :
- Adult
Male
medicine.medical_specialty
Cross-sectional study
Immunology
Population
urologic and male genital diseases
Psoriatic arthritis
Rheumatology
Troponin T
Diabetes mellitus
Internal medicine
medicine
Immunology and Allergy
Humans
Prospective Studies
education
Prospective cohort study
Aged
education.field_of_study
business.industry
Arthritis, Psoriatic
Middle Aged
medicine.disease
Cross-Sectional Studies
Cohort
Biomarker (medicine)
Population study
Female
business
Biomarkers
Subjects
Details
- ISSN :
- 1437160X
- Volume :
- 40
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Rheumatology international
- Accession number :
- edsair.doi.dedup.....1da2d90496cf31ccbddf2a291c0fbf6d