Routine childhood vaccinations did not increase the risk of incident type 1 diabetes in Danish children

Hviid A, Stellfeld M, Wohlfahrt J, et al . Childhood vaccination and type 1 diabetes. N Engl J Med 2004;350:1398–404. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Q Are routinely administered childhood vaccines associated with an increased incidence of type 1 diabetes mellitus in a cohort of Danish children? ### ![Graphic][5] Design: a cohort study of children followed up from birth to a mean age of 6.4 years. ### ![Graphic][6] Setting: Denmark. ### ![Graphic][7] Participants: 739 694 children born in Denmark from January 1990 to December 2000. ### ![Graphic][8] Risk factors: vaccinations with any of 6 groups of vaccines including Haemophilus influenza type b; diphtheria, tetanus, and inactivated poliovirus; diphtheria, tetanus, acellular pertussis, and inactivated poliovirus; whole cell pertussis; measles, mumps, and rubella; and oral poliovirus (data from vaccination reports of the National Board … [1]: {openurl}?query=rft.jtitle%253DNew%2BEngland%2BJournal%2Bof%2BMedicine%26rft.stitle%253DNEJM%26rft.issn%253D0028-4793%26rft.aulast%253DHviid%26rft.auinit1%253DA.%26rft.volume%253D350%26rft.issue%253D14%26rft.spage%253D1398%26rft.epage%253D1404%26rft.atitle%253DChildhood%2BVaccination%2Band%2BType%2B1%2BDiabetes%26rft_id%253Dinfo%253Adoi%252F10.1056%252FNEJMoa032665%26rft_id%253Dinfo%253Apmid%252F15070789%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1056/NEJMoa032665&link_type=DOI [3]: /lookup/external-ref?access_num=15070789&link_type=MED&atom=%2Febnurs%2F7%2F4%2F121.atom [4]: /lookup/external-ref?access_num=000220562500006&link_type=ISI [5]: /embed/inline-graphic-1.gif [6]: /embed/inline-graphic-2.gif [7]: /embed/inline-graphic-3.gif [8]: /embed/inline-graphic-4.gif