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[Treatment of hepatosplenic candidiasis with liposomal amphotericin B in a patient with acute leukemia; a case report of the experience of use of liposomal amphotericin B]
- Source :
- Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 72(6)
- Publication Year :
- 1998
-
Abstract
- We report a 26-year-old male patient with acute myelocytic leukemia and hepatosplenic candidiasis during his clinical course. His hepatosplenic candidiasis was refractoty to itraconazole and fluconazol. He developed serious side-effect such as renal dysfunction, when conventional amphotericin B was given. Then he was treated with liposomal amphotericin B (Abelcet). This therapy was safe and effective for him. He was able to be treated with 3075 mg of a liposomal amphotericin B. This was ten times as much as the dose of conventional amphotericin B which was given earlier until amphotericin B was stopped because of renal dysfunction. Liposomal amphotericin B seems to be a safe and effective therapy for systemic fungal infectin and should be considered more in Japan.
- Subjects :
- Adult
Male
medicine.medical_specialty
Antifungal Agents
Itraconazole
Liver Abscess
Gastroenterology
Internal medicine
Amphotericin B
Medicine
Humans
Splenic Diseases
Acute leukemia
business.industry
Clinical course
Candidiasis
General Medicine
bacterial infections and mycoses
Leukemia, Myeloid, Acute
Male patient
Liposomes
Myelocytic leukemia
Liposomal amphotericin
business
medicine.drug
Subjects
Details
- ISSN :
- 03875911
- Volume :
- 72
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
- Accession number :
- edsair.doi.dedup.....1d5f00e680524c591d0bb3049d97dce6