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Socioeconomic Conditions in Childhood, Adolescence, and Adulthood and the Risk of Ischemic Stroke
- Source :
- Stroke. 47(1)
- Publication Year :
- 2015
-
Abstract
- Background and Purpose— The association between socioeconomic status in adulthood and the risk of stroke is well established; however, the independent effects of socioeconomic conditions in different life phases are less understood. Methods— Within a population-based stroke registry, we performed a case–control study with 470 ischemic stroke patients (cases) aged 18 to 80 years and 809 age- and sex-matched stroke-free controls, randomly selected from the population (study period October 2007 to April 2012). We assessed socioeconomic conditions in childhood, adolescence, and adulthood, and developed a socioeconomic risk score for each life period. Results— Socioeconomic conditions were less favorable in cases regarding paternal profession, living conditions and estimated family income in childhood, school degree, and vocational training in adolescence, last profession, marital status and periods of unemployment in adulthood. Using tertiles of score values, low socioeconomic conditions during childhood (odds ratio 1.77; 95% confidence interval 1.20–2.60) and adulthood (odds ratio 1.74; 95% confidence interval 1.16–2.60) but not significantly during adolescence (odds ratio 1.64; 95% confidence interval 0.97–2.78) were associated with stroke risk after adjustment for risk factors and other life stages. Medical risk factors attenuated the effect of childhood conditions, and lifestyle factors reduced the effect of socioeconomic conditions in adolescence and adulthood. Unfavorable childhood socioeconomic conditions were particularly associated with large artery atherosclerotic stroke in adulthood (odds ratio 2.13; 95% confidence interval 1.24–3.67). Conclusions— This study supports the hypothesis that unfavorable childhood socioeconomic conditions are related to ischemic stroke risk, independent of established risk factors and socioeconomic status in adulthood, and fosters the idea that stroke prevention needs to begin early in life.
- Subjects :
- Adult
Male
Pediatrics
medicine.medical_specialty
Adolescent
Population
Family income
Brain Ischemia
03 medical and health sciences
Young Adult
0302 clinical medicine
Risk Factors
Germany
medicine
Humans
030212 general & internal medicine
Registries
Young adult
education
Child
Socioeconomic status
Stroke
Aged
Advanced and Specialized Nursing
education.field_of_study
Framingham Risk Score
business.industry
Case-control study
Age Factors
Middle Aged
medicine.disease
Social Class
Socioeconomic Factors
Case-Control Studies
Marital status
Female
Neurology (clinical)
Cardiology and Cardiovascular Medicine
business
030217 neurology & neurosurgery
Demography
Subjects
Details
- ISSN :
- 15244628
- Volume :
- 47
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Stroke
- Accession number :
- edsair.doi.dedup.....1d398be90e8d3e78ee63ef71916d4eeb