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MiRNAs of peripheral blood as the biomarker of schizophrenia
- Source :
- Hereditas, Hereditas, Vol 155, Iss 1, Pp 1-5 (2017)
- Publication Year :
- 2017
- Publisher :
- BioMed Central, 2017.
-
Abstract
- The diagnosis of schizophrenia is currently based on the symptoms and bodily signs rather than on the pathological and physiological markers of the patient. In the search for new molecular targeted therapy medicines, and recurrence of early-warning indicators have become the major focus of contemporary research, because they improve diagnostic accuracy. Biomarkers reflect the physiological, physical and biochemical status of the body, and so have extensive applicability and practical significance. The ascertainment of schizophrenia biomarkers will help diagnose, stratify of disease, and treat of schizophrenia patients. The detection of biomarkers from blood has become a promising area of schizophrenia research. Recently, a series of studies revealed that, MiRNAs play an important role in the genesis of schizophrenia, and their abnormal expressions have the potential to be used as biomarkers of schizophrenia. This article presents and summarizes the value of peripheral blood miRNAs with abnormal expression as the biomarker of schizophrenia.
- Subjects :
- 0301 basic medicine
lcsh:QH426-470
Schizophrenia (object-oriented programming)
medicine.medical_treatment
Disease
Review
Biology
Bioinformatics
behavioral disciplines and activities
Targeted therapy
03 medical and health sciences
0302 clinical medicine
microRNA
mental disorders
Genetics
medicine
Peripheral MiRNAs
Humans
Significance and values
Pathological
General Medicine
Peripheral blood
lcsh:Genetics
MicroRNAs
030104 developmental biology
Schizophrenia
Biomarker (medicine)
030217 neurology & neurosurgery
Biomarkers
Diagnosis of schizophrenia
Subjects
Details
- Language :
- English
- ISSN :
- 16015223 and 00180661
- Volume :
- 155
- Database :
- OpenAIRE
- Journal :
- Hereditas
- Accession number :
- edsair.doi.dedup.....1d14995676a85a03e2ffeb05f0fcaeaa