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Oxygen reserve index as a noninvasive indicator of arterial partial pressure of oxygen in anaesthetized donkeys: a preliminary study

Authors :
Brighton T. Dzikiti
Felix R. Algarin Sepulveda
Giulia Maria De Benedictis
Luca Bellini
Jill K. Maney
Source :
Veterinary anaesthesia and analgesia. 48(3)
Publication Year :
2020

Abstract

Objective To evaluate the oxygen reserve index (ORI) as a noninvasive estimate of the PaO2 during moderate hyperoxaemia [100–200 mmHg (13.3–26.6 kPa)], and to determine ORI values identifying PaO2 > 100, > 150 (20.0 kPa) and > 200 mmHg in anaesthetized donkeys with an inspired fraction of oxygen (F i O2) > 0.95. Study design Prospective observational study. Animals A group of 28 adult standard donkeys aged (mean ± standard deviation) 4 ± 2 years and weighing 135 ± 15 kg. Methods Donkeys were sedated intramuscularly with xylazine and butorphanol; anaesthesia was induced with ketamine and diazepam and maintained with isoflurane in oxygen. An adhesive sensor probe was applied to the donkey’s tongue and connected to a Masimo pulse co-oximeter to determine ORI values. An arterial catheter was inserted into an auricular artery. After ORI signal stabilization, the value was noted and PaO2 determined by blood gas analysis. The Pearson correlation coefficient was used to assess the relationship between ORI and PaO2 for oxygen tension 150 and 200 mmHg (20.0 and 26.6 kPa) with the highest sensitivity and specificity. Results A total of 106 paired measurements were collected. A mild positive correlation was observed between ORI and PaO2 for values 0.0, > 0.1 and > 0.3 indicated a PaO2 > 100, > 150 and > 200 mmHg (13.3, 20.0 and 26.6 kPa) with negative predictive values > 94%. Conclusions and clinical relevance ORI may provide a noninvasive indication of PaO2 > 100, > 150 and > 200 mmHg (13.3, 20.0 and 26.6 kPa) in anaesthetized donkeys with an F i O2 > 0.95, although it does not replace blood gas analysis for assessment of oxygenation.

Details

ISSN :
14672995
Volume :
48
Issue :
3
Database :
OpenAIRE
Journal :
Veterinary anaesthesia and analgesia
Accession number :
edsair.doi.dedup.....1cc70aad78c9f37a0947a07b37f37013