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The current potential of high‐intensity focused ultrasound for pancreatic carcinoma

Authors :
Kota Yamada
Toshio Kurihara
Takayoshi Tsuchiya
Fuminori Moriyasu
Fumihide Itokawa
Shujiro Tsuji
Takatomo Sano
Atsushi Sofuni
Kentaro Ishii
Takao Itoi
Source :
Journal of Hepato-Biliary-Pancreatic Sciences. 18:295-303
Publication Year :
2011
Publisher :
Wiley, 2011.

Abstract

Pancreatic carcinoma has one of the poorest prognoses among malignant tumors. Many pancreatic carcinoma patients who undergo common treatments, such as surgery, radio-chemotherapy and chemotherapy, gained little benefit because of the histological characteristics.HIFU is a new technique of noninvasive treatment for unresectable pancreatic carcinoma. HIFU has the ability to ablate the deep tissues inside body from an external source using high-intensity focused ultrasound. The effects of HIFU can result in cell destruction and tissue necrosis.Results from study in China in 251 patients with advanced pancreatic carcinoma suggested that HIFU treatment could reduce the size of tumors without causing complications and prolong survival. Moreover, according to some reports from China, HIFU treatment is suggested to be useful as the one of palliative treatments for unresectable pancreatic carcinoma. Our case of HIFU therapy for pancreatic carcinoma is presented including pathological findings in this paper. The results suggested that HIFU treatment might be effective in controlling local tumor.HIFU therapy may have the possibility of becoming one of the combination therapies for treating pancreatic carcinoma in the future.

Details

ISSN :
18686982 and 18686974
Volume :
18
Database :
OpenAIRE
Journal :
Journal of Hepato-Biliary-Pancreatic Sciences
Accession number :
edsair.doi.dedup.....1c71b956e2b7a8fae515edc812220411
Full Text :
https://doi.org/10.1007/s00534-010-0355-4