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Triazinyl porphyrin-based photoactive cotton fabrics: preparation, characterization, and antibacterial activity

Authors :
Matthieu Barrière
Vincent Sol
Robert Granet
Céline Frochot
Naïma Saad
Cyril Ringot
Pierre Krausz
Pierre Couleaud
Philippe Bressollier
Laboratoire de Chimie des Substances Naturelles (LCSN)
Université de Limoges (UNILIM)-Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503)
Médicaments Photoactivables - Photochimiothérapie (PHOTOMED)
Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Laboratoire Réactions et Génie des Procédés (LRGP)
Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)
Conseil Régional du Limousin
Dr. Michel Guilloton and Pierre Carles (SPCTS-Limoges) for MEB Analysis
Source :
Biomacromolecules, Biomacromolecules, American Chemical Society, 2011, 12 (5), pp.1716-1723. ⟨10.1021/bm200082d⟩
Publication Year :
2011
Publisher :
HAL CCSD, 2011.

Abstract

International audience; In the present work, we report on the synthesis of cellulose cotton fibers bearing different types of photosensitizers with the aim to prepare new efficient polymeric materials for antimicrobial applications. Anionic, neutral, and cationic amino porphyrins have been covalently grafted on cotton fabric, without previous chemical modification of the cellulosic support, using a 1,3,5-triazine derivative as the linker. The obtained porphyrin-grafted cotton fabrics were characterized by infrared (ATR-FTIR), diffuse reflectance UV-vis (DRUV) spectroscopies, and thermogravimetric analysis (TGA) to confirm the triazine linkage. Antimicrobial activity of porphyrin-cellulose materials was tested under visible light irradiation against Staphylococcus aureus and Escherichia coli . The results showed excellent activity on the Gram-positive bacterium, showing structure-activity relationship, although no photodamage of the Gram-negative microorganism was recorded. A mechanism of bacterial inactivation by photosensitive surfaces is proposed.

Details

Language :
English
ISSN :
15257797 and 15264602
Database :
OpenAIRE
Journal :
Biomacromolecules, Biomacromolecules, American Chemical Society, 2011, 12 (5), pp.1716-1723. ⟨10.1021/bm200082d⟩
Accession number :
edsair.doi.dedup.....1c424d79d79b1db6e2d677c65492c9c4
Full Text :
https://doi.org/10.1021/bm200082d⟩