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Single DNA/protein studies with magnetic traps
- Source :
- Current Opinion in Structural Biology. 19:615-622
- Publication Year :
- 2009
- Publisher :
- Elsevier BV, 2009.
-
Abstract
- Magnetic traps provide a simple technique to pull and twist a variety of biomolecules and monitor the resulting change in extension. They have been used with great success to investigate the interaction of stretched and supercoiled DNA and DNA fibers (e.g. chromatin) with a great variety of enzymes. In this small review we will address their recent use in the study of topoisomerases, gyrase, DNA translocases and various structural proteins.
- Subjects :
- chemistry.chemical_classification
Biomolecule
Topoisomerase
Protein dna
DNA, Single-Stranded
Proteins
Nanotechnology
Plasma protein binding
Biology
Biochemistry
DNA gyrase
Enzymes
Chromatin
Magnetics
chemistry.chemical_compound
chemistry
Structural Biology
biology.protein
Biophysics
Animals
Humans
DNA supercoil
Molecular Biology
DNA
Protein Binding
Subjects
Details
- ISSN :
- 0959440X
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Current Opinion in Structural Biology
- Accession number :
- edsair.doi.dedup.....1c162fc46b997ca5a170251b7e8d38ea