Back to Search Start Over

Pyrrole: An insight into recent pharmacological advances with structure activity relationship

Authors :
Ozair Alam
Muzaffar Iqbal
Shujauddin Ahmad
Mohd. Javed Naim
Mohammad Mumtaz Alam
Mohammad Shaquiquzzaman
Source :
European Journal of Medicinal Chemistry. 157:527-561
Publication Year :
2018
Publisher :
Elsevier BV, 2018.

Abstract

Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for the generation of library of enormous lead molecules. Owing to its vast pharmacological profile, pyrrole and its analogues have drawn much attention of the researchers/chemists round the globe to be explored exhaustively for the benefit of mankind. This review focusses on recent advancements; pertaining to pyrrole scaffold, discussing various aspects of structure activity relationship and its bioactivities.

Details

ISSN :
02235234
Volume :
157
Database :
OpenAIRE
Journal :
European Journal of Medicinal Chemistry
Accession number :
edsair.doi.dedup.....1bae3abe72a8a0a6ee92d5260e639f6d