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One undescribed glycoside benzofuran derivative and a new p-hydroxybenzoate glycoside from the leaves of Illicium dunnianum Tutcher

Authors :
He, Xiao-qing
Li, Hai-bo
Li, Ting
Chen, Xin-yin
Wang, Zhen-zhong
Yao, Xin-sheng
Xiao, Wei
Yu, Yang
Publication Year :
2023
Publisher :
Taylor & Francis, 2023.

Abstract

One undescribed benzofuran derivative (illiciumphenolicacid A, 1) and one new phenolic glycoside (illiciumphenolicacid B, 2), together with six known compounds (3–8) were isolated from the leaves of Illicium dunnianum Tutcher. Their structures were elucidated by detailed spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR). In addition, we determined the α-glucosidase inhibitory activity of the isolates in vitro using spectrophotometric methods. Compared with the positive control acarbose (IC50 306.2 ± 4.1 μM), compounds 1–8 were shown to be moderate potential α-glucosidase inhibitory activity with IC50 values in the range 380–655 μM.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....1b8be1237f4080d1b0bf3d87a7f3fd2e
Full Text :
https://doi.org/10.6084/m9.figshare.23284176