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Carbetocin in prevention of postpartum hemorrhage: Experience in a tertiary medical center of Taiwan
- Source :
- Taiwanese Journal of Obstetrics & Gynecology, Vol 55, Iss 6, Pp 804-809 (2016)
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Objective: The aim of this retrospective observational study was to determine the efficacy of carbetocin in reducing blood loss and primary postpartum hemorrhage (PPH) in vaginal and cesarean deliveries in a tertiary hospital in Taiwan. Materials and methods: Eligible gravid women (27–41 weeks) with available data were categorized into those treated prophylactically with and without carbetocin. The primary outcome was blood loss and incidence of primary PPH as measured by intrapartum/intraoperative and postpartum (recovery room) blood loss. Results: A total of 1069 deliveries were evaluated. Maternal age (∼31 years of age), body mass index (∼27 kg/m2) and parity (∼1.4) were similar among those treated with and without carbetocin for both vaginal and cesarean deliveries. The majority [749/1069 (70.1%)] of deliveries were vaginal; a similar proportion of women undergoing vaginal [221/749 (29.5%)] and cesarean [110/320 (34.4%)] deliveries received prophylactic carbetocin for prevention of PPH. Among vaginal deliveries, there was no significant difference in intrapartum (p = 0.083) or postpartum (p = 0.925) blood loss, or incidence of PPH (p = 0.092) between women with versus without carbetocin prophylaxis. However, there was a significant reduction in the intraoperative and total blood loss among cesarean deliveries with versus without carbetocin prophylaxis (p
- Subjects :
- Adult
medicine.medical_specialty
Taiwan
Gestational Age
Oxytocin
lcsh:Gynecology and obstetrics
03 medical and health sciences
0302 clinical medicine
Primary outcome
Blood loss
Primary postpartum hemorrhage
Pregnancy
Oxytocics
Obstetrics and Gynaecology
carbetocin
medicine
Humans
blood loss
030212 general & internal medicine
lcsh:RG1-991
reproductive and urinary physiology
Retrospective Studies
Gynecology
Chi-Square Distribution
030219 obstetrics & reproductive medicine
cesarean section
business.industry
Vaginal delivery
Obstetrics
Incidence
Significant difference
Obstetrics and Gynecology
Retrospective cohort study
Delivery, Obstetric
postpartum hemorrhage
Administration, Intravenous
Female
Carbetocin
vaginal delivery
business
Body mass index
medicine.drug
Subjects
Details
- ISSN :
- 10284559
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- Taiwanese Journal of Obstetrics and Gynecology
- Accession number :
- edsair.doi.dedup.....1b807d29a45a3a38202802cea56d337f