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Malakoplakia after kidney transplantation: Case report and literature review
- Source :
- Transplant infectious disease : an official journal of the Transplantation Society. 19(5)
- Publication Year :
- 2016
-
Abstract
- Malakoplakia is a granulomatous disease associated with an infectious etiology, usually involving the urinary tract. It reveals itself as a recurrent urinary tract infection (r-UTI), and in some cases, it is associated with impairment of renal function. Immunosuppression is one of its main associated factors, and it has been increasingly described in patients with solid organ transplantation (SOT), mainly kidney transplantation. Macroscopically, it can form masses and sometimes it may be confused with neoplasia, which is why histological findings are fundamental for the diagnosis. Here, we present a case of bladder malakoplakia, manifested by r-UTI from Escherichia coli in a patient with renal transplantation, refractory to long-term antibiotic treatment and reduction in immunosuppression, which resolved after surgical management. We also summarize the clinical characteristics of malakoplakia and compare them with previous reports in the literature on SOT.
- Subjects :
- Pathology
medicine.medical_specialty
medicine.medical_treatment
Urinary system
030232 urology & nephrology
Renal function
Malacoplakia
urologic and male genital diseases
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Kidney transplantation
Transplantation
business.industry
Urinary Bladder Diseases
Malakoplakia
Immunosuppression
Middle Aged
medicine.disease
Kidney Transplantation
Infectious Diseases
030220 oncology & carcinogenesis
Female
Urinary bladder disease
business
Subjects
Details
- ISSN :
- 13993062
- Volume :
- 19
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Transplant infectious disease : an official journal of the Transplantation Society
- Accession number :
- edsair.doi.dedup.....1b234e3ec19777ac98d033fd539e0473