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Endovascular thrombectomy in young patients with stroke

Authors :
Johannes M Weller
Franziska Dorn
Julius N Meissner
Sebastian Stösser
Niklas M Beckonert
Julia Nordsiek
Christine Kindler
Milani Deb-Chatterji
Gabor C Petzold
Felix J Bode
A. Reich
O. Nikoubashman
J. Röther
B. Eckert
M. Braun
G.F. Hamann
E. Siebert
C.H. Nolte
G. Bohner
R.M. Eckert
J. Borggrefe
P. Schellinger
J. Berrouschot
A. Bormann
C. Kraemer
H. Leischner
M. Petersen
F. Stögbauer
T. Boeck-Behrens
S. Wunderlich
A. Ludolph
K.H. Henn
C. Gerloff
J. Fiehler
G. Thomalla
A. Alegiani
J.H. Schäfer
F. Keil
S. Tiedt
L. Kellert
C. Trumm
U. Ernemann
S. Poli
J. Liman
M. Ernst
K. Gröschel
T. Uphaus
Source :
International Journal of Stroke. 18:453-461
Publication Year :
2022
Publisher :
SAGE Publications, 2022.

Abstract

Background: Endovascular treatment (ET) is standard of care in patients with acute ischemic stroke due to large vessel occlusion, but data on ET in young patients remain limited. Aim: We aim to compare outcomes for young stroke patients undergoing ET in a matched cohort. Methods: We analyzed patients from an observational multicenter cohort with acute ischemic stroke and ET, the German Stroke Registry—Endovascular Treatment trial. Baseline characteristics, procedural parameters, and functional outcome at 90 days were compared between young (Results: Out of 6628 acute ischemic stroke patients treated with ET, 363 (5.5%) were young. Young patients differed with regard to prognostic outcome characteristics. Specifically, National Institutes of Health Stroke Scale (NIHSS) at admission was lower (median 13, interquartile range (IQR) 8–17 vs. 15, IQR 9–19, p Conclusion: Young stroke patients undergoing ET have better outcomes compared to older patients, even when matched for prestroke condition, comorbidities, and stroke severity. Hence, more liberal guidelines to perform ET for younger patients may have to be established by future studies.

Subjects

Subjects :
Neurology

Details

ISSN :
17474949 and 17474930
Volume :
18
Database :
OpenAIRE
Journal :
International Journal of Stroke
Accession number :
edsair.doi.dedup.....1b03a31054db51e94697ad9de96da0ed
Full Text :
https://doi.org/10.1177/17474930221119602