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Association between intraoperative hypotension and postoperative myocardial injury in patients with prior coronary stents undergoing high-risk surgery: a retrospective study
- Source :
- Journal of Anesthesia. 34:257-267
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- We conducted a single-center retrospective study to evaluate the effects of intraoperative hypotension (IOH) on postoperative myocardial injury during major noncardiac surgery in patients with prior coronary stents with preoperatively normal cardiac troponin I levels. Although IOH is assumed to increase the risk of postoperative myocardial injury in patients with prior coronary stents, the level and duration of hazardous low blood pressure have not been clarified. Of 2517 patients with prior coronary stents undergoing noncardiac surgery between January 2010 and March 2017, we analyzed 195 undergoing major surgery (vascular, abdominal, and thoracic surgery) who had a normal preoperative high-sensitivity cardiac troponin I (hs-cTnI) level and were followed up postoperatively within 3 days. Postoperative myocardial injury was defined as a hs-cTnI level greater than the 99th percentile reference value. Primary IOH exposure was defined as a decrease of ≥ 50%, 40%, or 30% from the preinduction mean blood pressure. Additional definition of IOH was absolute mean blood pressure
- Subjects :
- Inotrope
medicine.medical_specialty
medicine.medical_treatment
Cohort Studies
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
030202 anesthesiology
Anesthesiology
Coronary stent
medicine
Humans
Intraoperative Complications
Retrospective Studies
business.industry
030208 emergency & critical care medicine
Retrospective cohort study
Vascular surgery
Anesthesiology and Pain Medicine
Blood pressure
Mean blood pressure
Cardiothoracic surgery
Anesthesia
Stents
Hypotension
business
Subjects
Details
- ISSN :
- 14388359 and 09138668
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Journal of Anesthesia
- Accession number :
- edsair.doi.dedup.....1b029340acaabec68f3643c8bd8a75a0