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Inhibitory control deficits in childhood and risk for substance use disorders: a review
- Source :
- The American journal of drug and alcohol abuse. 34(3)
- Publication Year :
- 2008
-
Abstract
- Identification of neurobiological factors that confer risk for the development of addiction may substantially advance development of new prevention and treatment strategies to combat substance use disorders. This review focuses on the relationship between impulsivity - a behavior that is common to the clinical picture of both substance use disorders (SUD) and childhood disruptive behavior disorders - and neurobiological risk for SUD. It further examines various behaviors within the over-arching domain of impulsivity, ultimately focusing on the more narrowly defined and measurable construct of inhibitory control, and concluding that underlying deficits in inhibitory control may be central to many of the behaviors associated with high risk for SUD. Targeted cross-sectional study of the neural basis of inhibitory dyscontrol in subjects at high risk for SUD, who have not yet begun to abuse drugs, has the potential to generate important hypotheses regarding the neurobiological underpinnings of SUD risk. Hypotheses developed using this approach can be more definitively evaluated in longitudinal studies with these same populations, extending through the period of maximal risk for SUD in adolescence and early adulthood.
- Subjects :
- medicine.medical_specialty
Adolescent
Substance-Related Disorders
media_common.quotation_subject
Vulnerability
Medicine (miscellaneous)
Impulsivity
behavioral disciplines and activities
Risk Factors
mental disorders
medicine
Humans
Psychiatry
Child
media_common
Addiction
Risk factor (computing)
medicine.disease
Substance abuse
Psychiatry and Mental health
Clinical Psychology
Inhibition, Psychological
Conduct disorder
Attention Deficit and Disruptive Behavior Disorders
Impulsive Behavior
medicine.symptom
Psychology
Construct (philosophy)
Psychopathology
Subjects
Details
- ISSN :
- 10979891
- Volume :
- 34
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The American journal of drug and alcohol abuse
- Accession number :
- edsair.doi.dedup.....1af5b2e37d72830ca26da4132ea6dd1e