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An analysis of factors associated with influenza, pneumoccocal, Tdap, and herpes zoster vaccine uptake in the US adult population and corresponding inter-state variability
- Source :
- Human Vaccines & Immunotherapeutics
- Publication Year :
- 2017
- Publisher :
- Informa UK Limited, 2017.
-
Abstract
- Despite longstanding recommendations for routine vaccination against influenza; pneumococcal; tetanus, diphtheria, acellular pertussis (Tdap); and herpes zoster (HZ) among the United States general adult population, vaccine uptake remains low. Understanding factors that influence adult vaccination and coverage variability beyond the national level are important steps toward developing targeted strategies for increasing vaccination coverage. A retrospective analysis was conducted using data from the Behavioral Risk Factor Surveillance System (2011–2014). Multivariable logistic regression modeling was employed to identify individual factors associated with vaccination (socio-demographics, health status, healthcare utilization, state of residence) and generate adjusted vaccination coverage and compliance estimates nationally and by state. Results indicated that multiple characteristics were consistently associated with a higher likelihood of vaccination across all four vaccines, including female sex, increased educational attainment, and annual household income. Model-adjusted vaccination coverage estimates varied widely by state, with inter-state variability for the most recent year of data as follows: influenza (aged ≥18 years) 30.2–49.5%; pneumococcal (aged ≥65 years) 64.0–74.7%; Tdap (aged ≥18 years) 18.7–46.6%; and HZ (aged ≥60 years) 21.3–42.9%. Model-adjusted compliance with age-appropriate recommendations across vaccines was low and also varied by state: influenza+Tdap (aged 18–59 years) 7.9–24.7%; influenza+Tdap+HZ (aged 60–64 years) 4.1–14.4%; and influenza+Tdap+HZ+pneumococcal (aged ≥65 years) 3.0–18.3%. In summary, after adjusting for individual characteristics associated with vaccination, substantial heterogeneity across states remained, suggesting that other local factors (e.g. state policies) may be impacting adult vaccines uptake. Further research is needed to understand such factors, focusing on differences between states with high versus low vaccination coverage.
- Subjects :
- Adult
Adolescent
Herpes Zoster Vaccine
Whooping Cough
Immunology
coverage
herpes zoster
Diphtheria-Tetanus-acellular Pertussis Vaccines
compliance
Pneumococcal Infections
Pneumococcal Vaccines
Young Adult
03 medical and health sciences
0302 clinical medicine
Influenza, Human
medicine
Humans
Immunology and Allergy
030212 general & internal medicine
Young adult
Whooping cough
Retrospective Studies
Pharmacology
Vaccines
Tetanus
030505 public health
Behavioral Risk Factor Surveillance System
business.industry
Diphtheria
Vaccination
Middle Aged
medicine.disease
Influenza
pneumococcal
state-level
United States
Tdap
Influenza Vaccines
0305 other medical science
business
Research Paper
Demography
Subjects
Details
- ISSN :
- 2164554X and 21645515
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Human Vaccines & Immunotherapeutics
- Accession number :
- edsair.doi.dedup.....1ad8d4037a8e71a434f9b182c95b0428