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Concentrations of select persistent organic pollutants across pregnancy trimesters in maternal and in cord serum in Trujillo, Peru
- Source :
- Chemosphere. 91:1426-1433
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- Although the production and use of some persistent organic pollutants (POPs) have been banned or highly restricted, human exposure remains a subject of investigation due to their environmental persistence. Physiological changes during pregnancy may affect the disposition of POPs in the mother’s body, and thus fetal exposure. Changes in serum concentrations of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) across pregnancy trimesters, and trans-placental transfer to the fetus were investigated. Seventy-nine pregnant women in Trujillo, Peru were recruited in the first trimester of pregnancy, and provided blood samples for the analysis of 35 PCB congeners, 9 OCPs, and 11 polybrominated biphenyl diethers (PBDEs). Subsequently, maternal blood samples were collected in the second (n = 64) and third trimesters (n = 59), and cord blood samples (n = 50) were collected at delivery. There were statistically significant changes across trimesters (p 60% of cord serum samples. Intra-individual correlations in maternal serum concentrations were high for most of the POPs (ρ = 0.62–0.99; p
- Subjects :
- Adult
Polybrominated biphenyl
Environmental Engineering
Adolescent
Health, Toxicology and Mutagenesis
Physiology
Article
Persistence (computer science)
Toxicology
Young Adult
Pregnancy
CORD SERUM
Surveys and Questionnaires
Peru
Halogenated Diphenyl Ethers
Humans
Environmental Chemistry
Medicine
Tissue Distribution
Pregnancy Trimesters
Maternal-Fetal Exchange
Pollutant
Fetus
business.industry
Public Health, Environmental and Occupational Health
General Medicine
General Chemistry
Middle Aged
Fetal Blood
medicine.disease
Polychlorinated Biphenyls
Pollution
Maternal Exposure
Cord blood
Environmental Pollutants
Female
business
Subjects
Details
- ISSN :
- 00456535
- Volume :
- 91
- Database :
- OpenAIRE
- Journal :
- Chemosphere
- Accession number :
- edsair.doi.dedup.....1ad66e9afd70382e195bd8ed856517fa