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Clinical and electrocardiographic variables associated with increased risk of ventricular septal defect in acute anterior myocardial infarction
Clinical and electrocardiographic variables associated with increased risk of ventricular septal defect in acute anterior myocardial infarction
- Source :
- The American journal of cardiology. 86(8)
- Publication Year :
- 2000
-
Abstract
- It is unknown whether the risk factors associated with the development of ventricular septal defect (VSD) after acute myocardial infarction (MI) remain the same when thrombolytic therapy is used, nor have specific electrocardiographic patterns of acute MI associated with the development of VSD been identified. Our study population included patients with an anterior MI enrolled in the GUSTO-I study. Baseline clinical data were collected prospectively for all patients. Patients in whom VSD was suspected by the local investigators at each site were evaluated retrospectively. Baseline clinical and electrocardiographic variables were compared between 2 groups: 10,847 patients without VSD (99.6%) and 48 patients with confirmed VSD (0.4%). Multivariate analysis showed the following clinical variables to be independent predictors of VSD: age (odds ratio [OR] 2.19, 95% confidence intervals [CI] 1.62 to 2.98; p
- Subjects :
- Male
congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
Myocardial Infarction
Infarction
Angina
Electrocardiography
Internal medicine
medicine
Humans
cardiovascular diseases
Myocardial infarction
Prospective Studies
Risk factor
Prospective cohort study
Aged
Ventricular Septal Rupture
medicine.diagnostic_test
business.industry
Odds ratio
Middle Aged
medicine.disease
Multivariate Analysis
Cardiology
Myocardial infarction complications
Female
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 00029149
- Volume :
- 86
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- The American journal of cardiology
- Accession number :
- edsair.doi.dedup.....1a968737ab007efaa35c687612c4c42d