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Clinical and Laboratory Findings of Middle East Respiratory Syndrome Coronavirus Infection
- Source :
- Japanese journal of infectious diseases. 72(3)
- Publication Year :
- 2018
-
Abstract
- There is a paucity of data regarding the differentiating characteristics of patients with laboratory-confirmed and those negative for Middle East respiratory syndrome coronavirus (MERS-CoV) in South Korea. This hospital-based retrospective study compared MERS-CoV-positive and MERS-CoV-negative patients. A total of seven positive patients and 55 negative patients with a median age of 43 years (P = 0.845) were included. No statistical differences were observed with respect to their sex and the presence of comorbidities. At the time of admission, headache (28.6% vs. 3.6%; odds ratio [OR], 10.60; 95% confidence interval [CI], 1.22-92.27), myalgia (57.1% vs. 9.1%; OR, 13.33; 95% CI, 2.30-77.24), and diarrhea (57.1% vs. 14.5%; OR, 7.83; 95% CI, 1.47-41.79) were common among MERS-CoV-positive patients. MERS-CoV-positive patients were more likely to have a low platelet count (164 ± 76.57 vs. 240 ± 79.87) and eosinophil (0.27 ± 0.43 vs. 2.13 ± 2.01; P = 0.003). Chest radiography with diffuse bronchopneumonia was more frequent in MERS-CoV-positive patients than in negative patients (100% vs. 62.5%; P = 0.491). The symptoms of headache, myalgia, and diarrhea, as well as laboratory characteristics, including low platelet counts and eosinophil, and chest X-ray showing diffuse bronchopneumonia might enhance the ability to detect patients in South Korea infected with MERS-CoV.
- Subjects :
- 0301 basic medicine
Microbiology (medical)
myalgia
Adult
Male
medicine.medical_specialty
Middle East respiratory syndrome coronavirus
030106 microbiology
medicine.disease_cause
Disease Outbreaks
03 medical and health sciences
0302 clinical medicine
Internal medicine
Republic of Korea
medicine
Humans
030212 general & internal medicine
Coronavirus
Aged
Retrospective Studies
business.industry
Sputum
Retrospective cohort study
General Medicine
Odds ratio
Middle Aged
medicine.disease
Confidence interval
Hospitals
Pneumonia
Diarrhea
Infectious Diseases
Middle East Respiratory Syndrome Coronavirus
Female
medicine.symptom
business
Coronavirus Infections
Subjects
Details
- ISSN :
- 18842836
- Volume :
- 72
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Japanese journal of infectious diseases
- Accession number :
- edsair.doi.dedup.....1a461a2ca0719dc42d30d89f3860fa29