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Immune Checkpoint Inhibitor Myocarditis With Normal Cardiac Magnetic Resonance Imaging: Importance of Cardiac Biopsy and Early Diagnosis

Authors :
Alban Redheuil
Philippe Rouvier
Joe-Elie Salem
Ariel Cohen
Charlotte Fenioux
Clément Cholet
Stéphane Ederhy
Service de Cardiologie [CHU Saint-Antoine]
CHU Saint-Antoine [AP-HP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
Service de pharmacologie médicale [CHU Pitié-Salpêtrière]
CHU Pitié-Salpêtrière [AP-HP]
Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Service de Radiologie [CHU Saint-Antoine]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)
Service de pathologie [CHU Pitié-Salpêtrière]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP]
Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN)
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP]
Source :
Canadian Journal of Cardiology, Canadian Journal of Cardiology, Elsevier, 2020, ⟨10.1016/j.cjca.2020.12.022⟩
Publication Year :
2020

Abstract

International audience; Immune checkpoint inhibitors (ICI) have improved the management and the prognosis of patients with cancer but are associated with an increased risk of toxicities that can affect every organ. ICI-associated myocarditis has a low incidence (

Subjects

Subjects :
Pathology
medicine.medical_specialty
Myocarditis
Lung Neoplasms
Immune checkpoint inhibitors
Biopsy
Magnetic Resonance Imaging, Cine
[SDV.CAN]Life Sciences [q-bio]/Cancer
Immune checkpoint inhibitor
030204 cardiovascular system & hematology
cardiac magnetic resonance
Endomyocardial biopsy
03 medical and health sciences
Electrocardiography
0302 clinical medicine
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Cardiac magnetic resonance imaging
polycyclic compounds
medicine
Cardiac biopsy
cancer
Humans
030212 general & internal medicine
Neoplasm Metastasis
Infusions, Intravenous
Immune Checkpoint Inhibitors
medicine.diagnostic_test
business.industry
Incidence (epidemiology)
Myocardium
Cancer
Middle Aged
medicine.disease
Ipilimumab
Troponin
3. Good health
Increased risk
Early Diagnosis
Nivolumab
Female
Cardiology and Cardiovascular Medicine
business
hormones, hormone substitutes, and hormone antagonists
Biomarkers

Details

ISSN :
19167075 and 0828282X
Volume :
37
Issue :
10
Database :
OpenAIRE
Journal :
The Canadian journal of cardiology
Accession number :
edsair.doi.dedup.....1a0a1df6239483ce8f8604aca400f463

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Authors Abstract Subjects Details