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Sensitisation to lipid transfer proteins in pollen – allergic adults with food allergy
- Source :
- Advances in Dermatology and Allergology, Vol 37, Iss 4, Pp 508-512 (2020), Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii
- Publication Year :
- 2020
- Publisher :
- Termedia Publishing House, 2020.
-
Abstract
- Introduction Food allergy affects 6-17% of Europeans and in 60% of the cases it is accompanied by inhalation allergy. This is due to two phenomena, namely co-sensitisation and cross-reactivity, which are caused by panallergens, such as lipid transfer proteins (LTP). These proteins are classified as defence proteins PR-14 and are responsible for protecting the plant from bacterial and fungal infections. Clinically, LTP allergy manifests with severe anaphylactic reactions or milder reactions, such as oral allergy syndrome. Aim To assess the incidence of specific IgE to components belonging to LTP based on molecular testing. Material and methods The study was conducted at the Department of Allergy, Clinical Immunology and Internal Diseases in Bydgoszcz, Poland. A total of 50 subjects participated in the study. Each subject had their asIgE levels determined with ImmunoCap ISAC. Results and conclusions Antigen-specific IgE antibodies to LTP components were identified in 24% of the subjects. In subjects with LTP allergy, adverse skin reactions were the most common after consumption of sensitising foods. Peach was the most common food allergen triggering these reactions. The Artemisia vulgaris component Art v 3 was the precursor of LTP allergy in our study population: the highest incidence and the highest mean levels of asIgE were demonstrated for this component.
- Subjects :
- Allergy
cross-reactivity
lipid transfer protein
Dermatology
medicine.disease_cause
Immunoglobulin E
Cross-reactivity
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Oral allergy syndrome
Food allergy
Immunology and Allergy
Medicine
Internal medicine
Artemisia vulgaris
Original Paper
food allergy
biology
business.industry
medicine.disease
biology.organism_classification
RC31-1245
allergenic components
RL1-803
Immunology
biology.protein
Population study
business
Plant lipid transfer proteins
Subjects
Details
- Language :
- English
- ISSN :
- 22990046
- Volume :
- 37
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Advances in Dermatology and Allergology
- Accession number :
- edsair.doi.dedup.....19e9e1c779766a856419dbf7d9c2165f