Supplementary Table 9 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

XLSX file - 9KB, Simulation of tumor mutational heterogeneity. Estimates are for the minimum number of cell replications required for two randomly chosen cells to possess the number of mutational differences observed in paired cell lines at a greater than 99% probability. Data were simulated using fixed mutation probabilities of 10-8 per base per cell replication for non-hypermutated and 10-6 for hypermutated MSI-H tumors.