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The influence of vitamin D on neurodegeneration and neurological disorders: a rationale for its physio-pathological actions
- Source :
- Current Pharmaceutical Design, Current Pharmaceutical Design, Bentham Science Publishers, 2020, 26, ⟨10.2174/1381612826666200316145725⟩, Current Pharmaceutical Design, 2020, 26, ⟨10.2174/1381612826666200316145725⟩
- Publication Year :
- 2020
- Publisher :
- HAL CCSD, 2020.
-
Abstract
- Vitamin D is a steroid hormone implicated in the regulation of neuronal integrity and many brain functions. Its influence, as a nutrient and a hormone, on the physiopathology of the most common neurodegenerative diseases is continuously emphasized by new studies. This review addresses what is currently known about the action of vitamin D on the nervous system and neurodegenerative diseases such as Multiple Sclerosis, Alzheimer’s disease, Parkinson’s disease and Amyotrophic Lateral Sclerosis. Further vitamin D research is necessary to understand how the action of this “neuroactive” steroid can help to optimize the prevention and treatment of several neurological diseases.
- Subjects :
- amyotrophic lateral sclerosis
Parkinson's disease
Multiple Sclerosis
medicine.medical_treatment
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
Disease
03 medical and health sciences
0302 clinical medicine
Alzheimer Disease
Drug Discovery
[SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]
Vitamin D and neurology
Medicine
Humans
Amyotrophic lateral sclerosis
Vitamin D
[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM]
ComputingMilieux_MISCELLANEOUS
030304 developmental biology
Pharmacology
0303 health sciences
business.industry
Multiple sclerosis
Settore BIO/12
Neurodegeneration
[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology
Vitamins
Alzheimer's disease
medicine.disease
3. Good health
neurodegenerative diseases
Steroid hormone
[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
business
Neuroscience
[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
030217 neurology & neurosurgery
Hormone
Subjects
Details
- Language :
- English
- ISSN :
- 13816128
- Database :
- OpenAIRE
- Journal :
- Current Pharmaceutical Design, Current Pharmaceutical Design, Bentham Science Publishers, 2020, 26, ⟨10.2174/1381612826666200316145725⟩, Current Pharmaceutical Design, 2020, 26, ⟨10.2174/1381612826666200316145725⟩
- Accession number :
- edsair.doi.dedup.....19e0164eefdbf9e17eb0be070b3b315f