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Rabies Virus Glycoprotein-Mediated Transportation and T Cell Infiltration to Brain Tumor by Magnetoelectric Gold Yarnballs

Authors :
Wei Cheng
Yu-Lin Su
Hao-Hsiang Hsu
Ya-Hui Lin
Li-An Chu
Wei-Chen Huang
Yu-Jen Lu
Chi-Shiun Chiang
Shang-Hsiu Hu
Source :
ACS nano. 16(3)
Publication Year :
2022

Abstract

T lymphocyte infiltration with immunotherapy potentially suppresses most devastating brain tumors. However, local immune privilege and tumor heterogeneity usually limit the penetration of immune cells and therapeutic agents into brain tumors, leading to tumor recurrence after treatment. Here, a rabies virus glycoprotein (RVG)-camouflaged gold yarnball (RVG@GY) that can boost the targeting efficiency at a brain tumor

Details

ISSN :
1936086X
Volume :
16
Issue :
3
Database :
OpenAIRE
Journal :
ACS nano
Accession number :
edsair.doi.dedup.....19c496a81f112f80a9c06e1548caa6dd