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COVID-19 in people living with human immunodeficiency virus: A case series of 33 patients
- Source :
- Infection
- Publication Year :
- 2020
- Publisher :
- Cold Spring Harbor Laboratory, 2020.
-
Abstract
- Introduction Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population. Methods Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome. Results Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir. Conclusions This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART.
- Subjects :
- 0301 basic medicine
Male
Pediatrics
Human immunodeficiency virus (HIV)
HIV Infections
medicine.disease_cause
Severity of Illness Index
0302 clinical medicine
Antiretroviral Therapy, Highly Active
Pandemic
Medicine
030212 general & internal medicine
Darunavir
Coinfection
virus diseases
General Medicine
Middle Aged
Viral Load
Antiretroviral therapy
AIDS
Infectious Diseases
Female
Coronavirus Infections
medicine.drug
Adult
Microbiology (medical)
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
030106 microbiology
Pneumonia, Viral
03 medical and health sciences
Betacoronavirus
Acquired immunodeficiency syndrome (AIDS)
Severity of illness
Antiretroviral treatment
Humans
Protease inhibitor (pharmacology)
Tenofovir
Pandemics
Survival analysis
Retrospective Studies
Original Paper
SARS-CoV-2
business.industry
COVID-19
HIV
Retrospective cohort study
medicine.disease
HIV infection
Survival Analysis
Regimen
business
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Infection
- Accession number :
- edsair.doi.dedup.....19a761b36601a21da48c492790bafb2e