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Salvage Neck Dissection for Cervical Recurrence of Nasopharyngeal Carcinoma
- Source :
- Archives of Otolaryngology - Head and Neck Surgery. 123:725-729
- Publication Year :
- 1997
- Publisher :
- American Medical Association (AMA), 1997.
-
Abstract
- Objective: To evaluate the effectiveness of salvage neck dissection as part of a multidisciplinary treatment approach in persistent or recurrent metastatic nasopharyngeal carcinoma, after failure of initial radiotherapy at the regional site. Design: A retrospective study of 31 patients treated during a 14-year period from March 1981 through May 1995, with a maximum follow-up of 152 months. Factors evaluated include patients' sex, age, and initial stage of tumor, mobility and number of nodal recurrences, surgical and pathological findings, and postoperative irradiation. Setting: Academic tertiary referral center. Patients: Twenty-six men and 5 women were studied; one patient had neck dissection to both sides of the neck on separate occasions, for a total of 32 operations. All patients had pathologically proved nasopharyngeal carcinoma and had been previously treated at the primary site and both sides of the neck with definitive radiotherapy. Intervention: Patients underwent a radical, modified radical, or level Iāsparing radical neck dissection. Main Outcome Measure: Surgical morbidity, time to recurrence at the regional site, and survival time. Results: Clinically, there was a disease predilection of 81% at levels II and V. Surgical morbidity was minimal. Regional control was achieved in 20 (65%) of the patients, and the overall 5-year survival was 67%. Tumor involvement of the posterior triangle musculature and spinal accessory nerve was associated with failure to control neck disease. Extracapsular nodal extension correlated with a poor survival outcome. Conclusion: Control of regional disease by salvage neck dissection when radiotherapy has failed is both safe and effective in properly selected patients. Arch Otolaryngol Head Neck Surg. 1997;123:725-729
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
Accessory nerve
medicine.medical_treatment
Taiwan
Carcinoma
medicine
Humans
Stage (cooking)
Aged
Neoplasm Staging
Retrospective Studies
Salvage Therapy
business.industry
Nasopharyngeal Neoplasms
Neck dissection
Retrospective cohort study
General Medicine
Middle Aged
medicine.disease
Survival Analysis
Surgery
Radiation therapy
Dissection
Otorhinolaryngology
Nasopharyngeal carcinoma
Head and Neck Neoplasms
Lymphatic Metastasis
Neck Dissection
Female
Neoplasm Recurrence, Local
business
Subjects
Details
- ISSN :
- 08864470
- Volume :
- 123
- Database :
- OpenAIRE
- Journal :
- Archives of Otolaryngology - Head and Neck Surgery
- Accession number :
- edsair.doi.dedup.....19a22e6ae530f885a307d3b5034edc2b