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Evaluating Bacterial Pathogenesis Using a Model of Human Airway Organoids Infected with Pseudomonas aeruginosa Biofilms

Authors :
Mingxing Tang
Shumin Liao
Jing Qu
Yixin Liu
Shuhong Han
Zhao Cai
Yunping Fan
Liang Yang
Shuo Li
Liang Li
Source :
Microbiology Spectrum. 10
Publication Year :
2022
Publisher :
American Society for Microbiology, 2022.

Abstract

Human airway organoids (HAOs) are an organotypic model of human airway mucociliary epithelium. The HAOs can closely resemble their origin organ in terms of epithelium architecture and physiological function.

Details

ISSN :
21650497
Volume :
10
Database :
OpenAIRE
Journal :
Microbiology Spectrum
Accession number :
edsair.doi.dedup.....19249fa35e3b229c964f8a537e396890
Full Text :
https://doi.org/10.1128/spectrum.02408-22