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Effect of the 2009 Influenza A(H1N1) Pandemic on Invasive Pneumococcal Pneumonia
- Source :
- The Journal of Infectious Diseases. 207:1135-1143
- Publication Year :
- 2013
- Publisher :
- Oxford University Press (OUP), 2013.
-
Abstract
- Background Because pneumococcal pneumonia was prevalent during previous influenza pandemics, we evaluated invasive pneumococcal pneumonia (IPP) rates during the 2009 influenza A(H1N1) pandemic. Methods We identified laboratory-confirmed, influenza-associated hospitalizations and IPP cases (pneumococcus isolated from normally sterile sites with discharge diagnoses of pneumonia) using active, population-based surveillance in the United States. We compared IPP rates during peak pandemic months (April 2009-March 2010) to mean IPP rates in nonpandemic years (April 2004-March 2009) and, using Poisson models, to 2006-2008 influenza seasons. Results Higher IPP rates occurred during the peak pandemic month compared to nonpandemic periods in 5-24 (IPP rate per 10 million: 48 vs 9 (95% confidence interval [CI], 5-13), 25-49 (74 vs 53 [CI, 41-65]), 50-64 (188 vs 114 [CI, 85-143]), and ≥65-year-olds (229 vs 187 [CI, 159-216]). In the models with seasonal influenza rates included, observed IPP rates during the pandemic peak were within the predicted 95% CIs, suggesting this increase was not greater than observed with seasonal influenza. Conclusions The recent influenza pandemic likely resulted in an out-of-season IPP peak among persons ≥5 years. The IPP peak's magnitude was similar to that seen during seasonal influenza epidemics.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Databases, Factual
Population
medicine.disease_cause
Severity of Illness Index
Young Adult
Influenza A Virus, H1N1 Subtype
Risk Factors
Internal medicine
Influenza, Human
Pandemic
Confidence Intervals
Odds Ratio
Influenza A virus
Humans
Immunology and Allergy
Medicine
Poisson Distribution
Child
education
Pandemics
Aged
education.field_of_study
business.industry
Middle Aged
Pneumonia, Pneumococcal
medicine.disease
United States
Confidence interval
Influenza A virus subtype H5N1
Hospitalization
Pneumonia
Streptococcus pneumoniae
Infectious Diseases
Child, Preschool
Population Surveillance
Pneumococcal pneumonia
Human mortality from H5N1
Female
Seasons
business
Subjects
Details
- ISSN :
- 15376613 and 00221899
- Volume :
- 207
- Database :
- OpenAIRE
- Journal :
- The Journal of Infectious Diseases
- Accession number :
- edsair.doi.dedup.....19248794712a57c7ab2bf4a43ea13747