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Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines
- Source :
- Haematologica. 92(10)
- Publication Year :
- 2007
-
Abstract
- We report an increased incidence of high relapse risk features in 157 APL Brazilian patients. Out of 134 patients treated with ATRA and anthracyclines, only 91 (67.9%) achieved remission because 43 (32%) died during induction. The death rate during consolidation was 10.5%. Bleeding complications were the most frequent cause of failure (21.6%).
- Subjects :
- Acute promyelocytic leukemia
Adult
Male
medicine.medical_specialty
Adolescent
medicine.medical_treatment
Tretinoin
Leukemia, Promyelocytic, Acute
Internal medicine
medicine
Humans
Anthracyclines
Child
neoplasms
Aged
Chemotherapy
Hematology
business.industry
Incidence (epidemiology)
Mortality rate
Middle Aged
medicine.disease
Surgery
Leukemia
Treatment Outcome
Child, Preschool
Drug Therapy, Combination
Female
Complication
business
Brazil
medicine.drug
Follow-Up Studies
Subjects
Details
- ISSN :
- 15928721
- Volume :
- 92
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Haematologica
- Accession number :
- edsair.doi.dedup.....192400c488ec8b6dfe6ce43265c1ad54