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Supplemental Figures 1-8 from Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma

Authors :
Bakhtiar Yamini
Ralph R. Weichselbaum
Nikolai N. Khodarev
Gustavo Larsen
Luis Nunez
Ruben Spretz
David R. Raleigh
Abhineet Uppal
Szymon J. Szymura
Kirk E. Cahill
Nassir M. Mansour
Wei Zhang
Clayton D. Crawley
Longtao Wu
Giovanna M. Bernal
David J. Voce
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Figure S1 shows the results of the p50 dependent gene expression analysis, Figure S2 shows MALAT1 expression in different GBM cell lines, Figure S3 demonstrates a schematic of putative binding sites on MALAT1, Figure S4 shows killing and survival studies in multiple GBM cell lines targeting MALAT1 with two distinct si-RNA sequences, Figure S5 demonstrates hindlimb xenograft growth following treatment with nanoparticles targeting MALAT1 and TMZ, Figure S6 shows in-situ hybridization of MALAT1, Figure S7 shows survival curves of GBM patients with differential MALAT1 expression, Figure S8 shows differential MALAT1 expression among GBM subtypes.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....191bd418e0c165e3170f860c1cc21eff
Full Text :
https://doi.org/10.1158/0008-5472.22418556